SciELO - Scientific Electronic Library Online

 
vol.29 número3Frecuencia de micronúcleos en eritrocitos con coloración secuencial Giemsa-naranja de acridina en el gato doméstico( Felis domesticus)Polimorfismos de los genes calpaína y calpastatina en el ganadocriollo colombiano Hartón del Valle índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

Compartilhar


Revista de Investigaciones Veterinarias del Perú

versão impressa ISSN 1609-9117

Resumo

MOYA-SALAZAR, Jeel; VERANO-ZELADA, Mario  e  VEGA-VERA, Rafael. Prevalence of chromosomal alterations in domestic dogs ( canis familiaris) with neoplasms: a prospective study. Rev. investig. vet. Perú [online]. 2018, vol.29, n.3, pp.808-817. ISSN 1609-9117.  http://dx.doi.org/10.15381/rivep.v29i3.13235.

The objective of this study was to determine the prevalence of chromosomal alterations in Canis familiaris with clinical neoplasms. Twenty-five patients from a veterinary clinic in Lima, Peru in 2015-2016 were monitored. Blood samples were collected by venous puncture for peripheral blood culture and chromosomal analysis and were stored for 3 ± 1 hours maximum. Cytogenetic processing and conventional GTG banding were performed. The report was made according to the recommendations of the Committee for the Standardized Karyotype of the Dog. The average age was 9.5 years (4-17 years) and the racial groups with greater frequency were the mestizo (20%), Golden Retriever (16%) and Shi-tzu (11.5%). Chromosomal alterations were observed in 72% of the patients. Of these, 9 (36%) were trisomies, 9 (36%) constitutive heterochromatins, 2 (8%) translocations, 2 (8%) deletions and 1 (4%) ring chromosome. Mixed alterations were observed in 9 patients (36%), where the trisomy of chromosome 13 was the most frequent (28%), followed by heterochromatin of chromosome 9 (24%). Risk analysis using multiple logistic regression showed that dogs 10 years of age and older had 2.4 times more cancer risk than younger dogs (p<0.05).

Palavras-chave : dogs; cytogenetic analysis; neoplasms; prevalence.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons