SciELO - Scientific Electronic Library Online

 
vol.29 número4Estudio comparativo de perfil lipídico y presión arterial en caninos delgados y con sobrepesoGeneración de un protocolo para la síntesis de nanopartículas de quitosano cargadas con florfenicol a través del método degelación iónica índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

Compartilhar


Revista de Investigaciones Veterinarias del Perú

versão impressa ISSN 1609-9117

Resumo

ARAGON-URREGO, Catherine; BARBOSA, Irma Ximena  e  ARISTIZABAL, Omar Leonardo. Effect of platelet-rich plasma on skin flaps in rabbits. Rev. investig. vet. Perú [online]. 2018, vol.29, n.4, pp.1184-1194. ISSN 1609-9117.  http://dx.doi.org/10.15381/rivep.v29i4.15351.

Autologous platelet concentrates (APC) has been used as an accelerator of cutaneous healing in veterinary medicine. The aim of this study was to evaluate the effect of an APC on skin flaps in rabbits (Oryctolagus cuniculus). Ten New Zealand male rabbits were randomly divided into a control group and an APC group. A rotating cutaneous flap was made in the thoraco-dorsal region of the right thoracic limb of the rabbits. Half of the rabbits received APC infiltrated under the flap. Biopsies were taken from the union of the flap with the recipient bed at 3, 7, 14, and 21 days post-surgery. The histological analysis of the inflammatory infiltrate was made, and the proliferation of fibroblasts and type of collagen formed was determined. A significant difference was observed in the neutrophil count, macrophages and fibroblasts. The histological analysis showed that a single application of CAP does not reduce the healing time in skin flaps; however, it promotes the formation of blood vessels and reduces the inflammatory infiltrate in rabbits throughout experimental time.

Palavras-chave : rabbit; autologous platelets concentrate; skin flap; wound healing.

        · resumo em Espanhol     · texto em Espanhol

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons