Abstract

LIRA, David et al. Eficacia y efectos adversos de la metoclopramida endovenosa en el tratamiento de las crisis de migrañaEffectiveness and adverse effects of intravenous metoclopramide in the treatment of migraine crisis. Rev Neuropsiquiatr [online]. 2014, vol.77, n.2, pp.104-109. ISSN 0034-8597.

Objectives: Determine the adverse effects of intravenous metoclopramide in the acute treatment of migraine attacks. Patients and methods: Were evaluated patients with a confirmed diagnosis of migraine according to the criteria of the International Headache Society, they attended with migraine crisis to emergency or outpatient neurology. Demographic data were collected and pain intensity was determined by visual analog scale (VAS ) from 0 to 10. Each patient was given intravenous metoclopramide diluted. We determined the efficacy in reducing pain intensity and the side effects. Results: 76 patients were evaluated, of 18 to 56 years old, 77,6 % were women. The average baseline VAS was 8,6 , after receiving metoclopramide EV 80,2 % had a reduction in VAS ≥ 50 %. The 92,1 % of patients had any adverse effects, were the most frequent psychomotor restlessness, drowsiness, insomnia and dizziness. Conclusions: Intravenous metoclopramide is an effective treatment in controlling migraine attacks and produces very common side effects such as psychomotor restlessness, drowsiness, insomnia and dizziness; it should be noted prior to administration.

Keywords : Headache; adverse effects; effectiveness; metoclopramide; migraine.

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