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Revista de Neuro-Psiquiatría

Print version ISSN 0034-8597


ARIAS-GUTIERREZ¹, Miguel et al. Antituberculosis drug-induced psychosis: a case associated with cycloserine. Rev Neuropsiquiatr [online]. 2014, vol.77, n.3, pp.179-183. ISSN 0034-8597.

Our country has a high prevalence of tuberculosis (morbidity in year 2012 was 105,2  cases per 100 000 people). In the treatment of this disease, a high number of diverse drug-related side-effects, with prevalent neuropsychiatric type, can be developed, because of the antibiotic polypharmacy required and other possible risk factors. From a case of cycloserine-induced psychosis, in a patient  with multidrug-resistant tuberculosis, we review the relevant literature and recommend individualized consideration on the withdrawal of the side-effect trigger medication versus the need to maintain the essential and appropriate antibiotic coverage.

Keywords : Cycloserine; tuberculosis; multidrug-resistant; psychoses; substance-induced; drug-related side effects and adverse reactions.

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