Abstract

CRUZADO, Lizardo; RIVERA-ENCINAS, María Teresa; REVILLA-ZUNIGA, Joshep A  and  SANCHEZ-FERNANDEZ, Miguel. High airway obstruction secondary to recurrent laryngeal dystonia induced by haloperidol and ziprasidone.. Rev Neuropsiquiatr [online]. 2015, vol.78, n.3, pp.176-181. ISSN 0034-8597.

Antipsychotic-induced acute dystonia is a frequent extrapyramidal effect secondary to the use of these drugs and, although its prevalence is lower with the use of atypical antipsychotics, several cases of such adverse reactions still arise. One of these extrapyramidal effects, laryngeal dystonia, is a problem that requires urgent treatment and may even be life-threatening. We here report the case of a young female patient with the diagnosis of paranoid schizophrenia who presented to our emergency room with psychomotor agitation and was treated with parenteral antipsychotics. She presented laryngeal dystonia induced by use of haloperidol, in first time, and then induced by ziprasidone, both drugs intramuscularly administered. Were view the relevant literature about this case and we recommend to avoid the subsequent use of parenteral antipsychotics if there is the antecedent of laryngeal dystonia, because of the significant risk of recurrence. Prior to this case report, there was only four cases of acute laryngeal dystonia induced by ziprasidone reported in the scientific literature.

Keywords : Airway obstruction; dystonia; haloperidol; antipsychotic agents; drug-related side effects and adverse reactions.

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