Abstract

VALERIANO-LORENZO, Elizabeth et al. Prognosis in Epilepsy’s surgery: Can Cognitive Reserve influence it?. Rev Neuropsiquiatr [online]. 2016, vol.79, n.1, pp.31-41. ISSN 0034-8597.

Up to one-third of individuals diagnosed as having epilepsy continue to have seizures despite appropriate anti-epileptic drug treatment. Patients with refractory localization-related epilepsy can be referred for presurgical evaluation, and resective surgery is considered an effective treatment for such cases. Predictive factors of a better outcome for epilepsy’s surgery are contradictory, and recommendations include a detailed assessment of cognitive performance before and after surgery; this process, however does not consider the evaluation of Cognitive Reserve (CR). The use of an instrument that assesses the CRof patient-candidates would increase the predictive power of neuropsychological assessment regarding post-surgical prognosis and outcome; in turn, it could contribute to research of neuroprotective factors in patients with a superior pre- and post-surgical profile of cognitive performance, and also allow knowing how the patient’s educational and occupational activity, and use of leisure time are affected by epilepsy and its post-surgical variations.

Keywords : Epilepsy; surgery; neuropsychology; cognitive reserve.

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