Abstract

RUIZ-GROSSO, Paulo; TOMATEO, David; VALENCIA, Alfredo  and  VEGA-DIENSTMAIER, Johann M. Low dose aripiprazole for excessive daytime sleepiness associated with the use of haloperidol: A case report. Rev Neuropsiquiatr [online]. 2018, vol.81, n.1, pp.47-53. ISSN 0034-8597.  http://dx.doi.org/https://doi.org/10.20453/rnp.v81i1.3273.

Daily somnolence is a frequent adverse event associated to the use of antipsychotic medication in patients with schizophrenia. We present the case of a 43 years old women with schizophrenia and pharmacological treatment for 24 years, who, at the start of the treatment, showed inadequate response to low potency classical antipsychotics, achieving clinical stability for more than 10 years with the use of haloperidol. However, she presented severe daily somnolence which significantly limited her functionality and quality of life. After the addition of 3.75 mg and later 7.5 mg of aripiprazole the somnolence improved in nearly 80% without exacerbation of psychotic symptoms

Keywords : Aripiprazole; schizophrenia; side-effects; antipsychotics; somnolence.

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