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Revista de Neuro-Psiquiatría

Print version ISSN 0034-8597


OSORIO-MARCATINCO, Víctor; CASTRO-SUAREZ, Sheila  and  MEZA-VEGA, María. Cognitive characteristics of patients with relapsing - remitting multiple sclerosis during relapse attended inNational Institute of Neurological Sciences 2014 - 2016. Rev Neuropsiquiatr [online]. 2018, vol.81, n.2, pp.58-64. ISSN 0034-8597.

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. It can manifest with a wide variety of symptoms. Cognitive involvement has a prevalence of approximately 45% during the disease. Objectives: To determine clinical characteristics of cognitive during relapse in hospitalized patients with relapsing - remitting MS. Methods: A cross-sectional description was made that included 13 patients diagnosed with MS, between January 2014 and December 2016 of National Institute of Neurological Sciences. The Peruvian version of Addenbrooke’s Cognitive Examination (ACE) was applied to the Peruvian version for cognitive exploration during hospitalization. The Kurtzke extended disability scale was used in the clinical evaluation. In the determination of psychiatric comorbidities, Hamilton’s depression and anxiety scale were used. Results: The average score of the ACE test was 89.62 points. The performance in each cognitive domain showed a trend of high scores. 38.46% had some degree of depression or anxiety. Cognitive impairment was present in 15.38%. Conclusions: Cognitive impairment was found in hospitalized patients with RR - MS. It is suggested to perform studies with larger samples, and after clinical relapses and steroid use.

Keywords : cognition; multiple sclerosis; recurrence.

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