Resumo

SALAZAR-SAAVEDRA, Yesenia M  e  SAAVEDRA-CASTILLO, Javier E. Factors associated to irritability in adults with depressive episode in Metropolitan Lima. Rev Neuropsiquiatr [online]. 2019, vol.82, n.1, pp.37-55. ISSN 0034-8597.  http://dx.doi.org/10.20453/rnp.v82i1.3483.

Objective: To determine factors associated to the presence of irritability in adults with depressive episode (DE) in Metropolitan Lima in 2012. Materials and methods: Database of the Epidemiological Study of Metropolitan Lima and Callao, carried out in 2012, was used to make an observational, correlational, cross-sectional study. A multistage probabilistic sample of 4445 adults of 18 years and older. The instruments were: MINI (International Neuropsychiatric Interview), Mental Health Questionnaire of Colombia (modified), modified brief EMBU, a questionnaire of adverse early experiences, Pittsburgh Sleep Quality Index and a sociodemographic data sheet. Descriptive statistics, simple and multivariate regression were used to estimate prevalence of adults with irritability in depressive episode (IDE) and to determine the association between IDE and independent variables. Results: The prevalence of IDE was 34.9%. A statistically significant association was found with: early age of onset of DE, greater severity of DE, presence of generalized anxiety disorder (GAD), abuse/dependence on alcohol, some depressive symptoms (such as self-reproach, concentration problems and suicidal indicators), violent behaviors, a lower quality of sleep, parenting styles of overprotection and favoritism, and the presence of adverse events before the age of 18. Conclusions: The possibility that irritability may be considered as a specifier of the depressive episode, would contribute to the development of strategies for its identification and clinical management.

Palavras-chave : Depressive episode; irritability; adults.

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