Abstract

VENCES, Miguel A.; SAQUISELA, Víctor V.; BARRETO-ACEVEDO, Elliot  and  ZUNIGA, Marco A.. Encephalitis NMDAR: Case report with a long - term follow-up. Rev Neuropsiquiatr [online]. 2020, vol.83, n.2, pp.110-115. ISSN 0034-8597.  http://dx.doi.org/10.20453/rnp.v83i2.3753.

Autoimmune encephalitis due to surface antineural antibodies covers a wide spectrum of clinical entities. Encephalitis due to antibodies against the surface antigen of the external portion of the N-methyl-D-aspartate receptor (RNMDA) is the most frequent and best characterized. The case of an adolescent with a clinical picture of neurosychiatric disorder and epileptic seizures of recent onset is presented: he had a positive response for anti-RNMDA antibodies, and a partial response to treatment with corticosteroid therapy and immunoglobulin; therefore, he received additional management with plasma exchange followed by maintenance therapy with immunoglobulin cycles, without the use of immunosuppressants. The results of a long-term follow-up are reported.

Keywords : Encephalitis; N-Methylaspartate; treatment outcome.

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