Abstract

ZELADA-RIOS, Laura et al. Atypical Alterations of cerebrospinal fluid in Guillain Barré Syndrome: Cases Reports. Rev Neuropsiquiatr [online]. 2021, vol.84, n.1, pp.64-68. ISSN 0034-8597.  http://dx.doi.org/10.20453/rnp.v84i1.3939.

Guillain-Barré syndrome shows a cyto-albuminologic dissociation in most patients. Pleocytosis or hypoglycorrhachia may defer the diagnosis, a reason for which an infectious etiology must be ruled out. Three cases of Guillain-Barré are described, whose cerebrospinal fluid tests showed limphocytic pleocytosis and persistently elevated protein concentration, while one of the cases also showed hypoglycorrhachia, and the classic cyto-albuminologic dissociation was only demonstrated in subsequent analysis. The neurophysiologic evaluation revealed an axonal disruption in all the patients. The atypical alterations in the context of acute flaccid paralysis warrant a retesting of the cerebrospinal fluid in order to rule out other etiologies, but without postponing the start of treatment.

Keywords : Cyto-albuminologic dissociation; hypoglycorrhachia; cerebrospinal fluid; pleocytosis; acute axonal polyradiculopathy; Guillain-Barré Syndrome.

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