Revista Medica Herediana
versión impresa ISSN 1018-130X
PALACIOS PORRAS, Hermógenes y SOLIS VILLANUEVA, José. Hiperthyroidism in pregnancy: Clinic characteristics and maternal, fetal and perinatal morbility and mortality.. Rev Med Hered [online]. 1995, vol.6, n.3, pp. 107-114. ISSN 1018-130X.
Objective: To find the prevalence, clinic characteristics of hyperthyroidism during pregnancy and is influence upon maternal, fetal and perinatal morbility and mortality. Material and methods: We included 29 patients with a diagnosis of hyperthyroidism and pregnancy fulfilling the inclusion criteria. The patients were divided in tow groups. Compensated hyperthyroidism during all or most part of pregnancy (Group I, n=11) and not compensated hyperthyroidism (Group II, n=18). Results: The prevalence of hyperthyroidism and pregnancy was 0.03%. Graves disease was present in 95.5% of cases; 62% presented nausea and vomits and 90% showed diffuse goiter of 40-60 gr. of weight. Comparing groups I and II, we observed that group II mothers had on the average, a higher heart frequency and smaller gain of weight (p<0.001 and p<0.002 respectively). The offspring of group II had the highest prematurity rate (5 of 7) and low body weight (p<0.003); all abortions (4), demised (2) and congenit malformations (2) occurred in this group. The treatment employed was metamizol in variable schedule (10-30 mg/day). We did not find any important adverse effect of treatment. Conclusions: No compensated hyperthyroidism during pregnancy produced greatest maternal, fetal and perinatal mobility and mortality. (Rev Med Hered 1995; 6: 107-114).
Palabras llave : Hyperthyroidism; pregnancy; symptoms,; signs; treatment..