Abstract

RECHKEMMER PRIETO, Adolfo; TOVAR MENA, Hernán  and  JEFFERSON CORTEZ, Luz. Premature ovarian insufficiency in infertile women at the Hospital Nacional Arzobispo Loayza.. Rev Med Hered [online]. 1995, vol.6, n.3, pp.115-120. ISSN 1018-130X.

Objective: To know the local incidence and clinical features of premature ovarian failure in infertile patients. Material and Methods: Descriptive, retrospective study was performed. We reviewed the clinical files of the patients evaluated at the infertility clinic of the Hospital Nacional Arzobispo Loayza (HNCH), in Lima, Perú, between January 1989 and March 1995. Results: The incidence of the disease was 1.45% (27 out of 1,75 infertile patients). Everybody had elevated FSH levels and 25 out of 27 had low estradiol levels. 11.11% and 14.8% had external genital and mammary glands hypotrophy, respectively. Ovary biopsy was performed in 7 patients; in six of them ovarian follicles were not found. In these patients, idiopatic premature ovarian failure was the most frequent diagnosis. Hormonal replacement therapy was the main treatment. Ovulation induction with menotropins in one patient was successful and resulted in a twin pregnancy. Conclusions: Premature ovarian failure was an infrequent pathology in infertile women at the HNAL; secondary amenorrhea was the most frequent symptom and a third had vasomotor symptoms. (Rev Med Hered 1995; 6: 115-120).

Keywords : Premature ovarian failure; infertility; ypergonadotropic hypogonadism..

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