Abstract

DIAZ PLASENCIA, Juan et al. Cancer of renal pelvis: clinical pathological findings and survival. Rev Med Hered [online]. 1998, vol.9, n.1, pp.3-9. ISSN 1018-130X.

Objective: Identify the clinicopathologic features and to determine the influence of clinical stage, histologic type and modality of treatment in the 5-year survival rate. Material and Methods: We reviewed the clinical charts of 16 patients with carcinoma of the renal pelvis treated at Belén Hospital, Trujillo, Peru, between 1966 to 1995. Aged ranged from 45 to 85 years, with a mean of 64.7 years. Eight patients were male and 8 were female. Results:Total length of time before presentation averaged 30 months. Hematuria (81.3%), and flank pain (37.5%) were the most common symptoms. Clinical examination revealed pallor (43.8%), and palpable mass (32.3%) in the majority of patients. Left kidney was the commonest site involved (56.3%). The exfoliate cytology (PAP) identified carcinoma cells in 28.6% of cases. Final staging was as follows: 31.2% stage I-II, and 68.8% stage III-IV, with a 5 year survival of 100%, and 0% respectively. The most common histologic type was the transitional cell carcinoma (75%), followed by the squamous cell carcinoma (18.7%), and adenocarcinoma (6.3%). The survival at 5 years in patients with the transitional cell carcinoma was 36%, and for all other histologic types was of 0%. Eleven patients underwent surgical treatment, 4 received surgical and radiation therapy, and one was treated with radiotherapy alone, with a 5-year survival of 19%, 75%, and 0% respectively. The 5-year survival for the entire group was of 32%. Conclusion: An early diagnosis and an adequate management using nephroureterectomy combined with incision of bladder cuff for renal pelvis tumors should be considered to obtain a longer survival. ( Rev Med Hered 1998; 9:3-9)

Keywords : Carcinoma; renal pelvis; clínico-pathologic picture; survival.

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