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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X

Abstract

VALDIVIA INFANTAS, Isaac et al. Eficacia del examen digital rectal de la próstata y antígeno prostático específico en la detección del cáncer de próstata . Rev Med Hered [online]. 2002, vol.13, n.4, pp.125-130. ISSN 1018-130X.

Objective: To assess the efficacy of the Rectal Digital Test (RDT) and the Prostate Specific Antigen (PSA) in the detection of prostate cancer. Material and methods: It has been made a retrospective study at the Hospital Nacional Cayetano Heredia (HNCH) for the period 1977 - 1999. Clinical records of the patients that went to the Urology Service presenting prostatic symptomatology and that fulfill the inclusion criteria were revised. The efficacy of the diagnosis trials was assessed with the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). There was assessed the association to any trial with the histologic differentiation level and the perineural infiltration. Results: From 112 patients only 80 could be evaluated, 46 (57.5%) patients confirmed prostate cancer by histologic study and 38(82.7%) of them presented abnormal RDT and PSA > 4 ng/ml. From 62 patients with abnormal RDT 40 (64.5%) of them presented cancer. The PSA >10 ng/ml was detected in 59 patients and 42 (71.27%) of them suffered from cancer. For an abnormal RDT and a PSA >4 ng/ml, the sensitivity was 0.95, the specificity 0.65, the PPV 0.76 and the NPV 0.73. Both positive trials were associated with a poor level of histologic differentiation. Conclusion: In the population studied the abnormal RDT and the PSA> 4 ng/ml are efficacy to detect prostate cancer. ( Rev Med Hered 2002; 13: 125-130 ).

Keywords : Prostate specific antigen; rectal digital test of the prostate; prostate cancer.

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