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vol.15 issue4Acute surgical abdomen in patients infected with the Human Immunodeficiency Virus at the Hospital Nacional Cayetano HerediaMorbidity and mortality of patients with tuberculosis hospitalized at the Tropical Medicine, Infectious Diseases and Dermatology Department at the Hospital Nacional Cayetano Heredia from Lima-Peru, between 1990 - 2000 author indexsubject indexarticles search
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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X

Abstract

VERDONCK BOSTEELS, Kristien et al. Association between infection with human T Cell lymphotrophic virus type I (HTLV-I) and mortality in hospitalized patients with tuberculosis. Rev Med Hered [online]. 2004, vol.15, n.4, pp.197-202. ISSN 1018-130X.

Peru is endemic for both human T-cell lymphotropic virus type I (HTLV-I) and tuberculosis (TBC). Objective: Assess the association between HTLV-I infection and mortality among inpatients with TBC. Material and Methods: Consecutive patients admitted to the Departments of Internal Medicine and Infectious, Tropical and Dermatological diseases of the Hospital Nacional Cayetano Heredia with a diagnosis of TBC were interviewed and they were tested for HTLV-I. The hospital registries were reviewed to determine the outcome of hospitalization. Clinical and epidemiological variables that were associated with death during hospitalization on univariate analysis were included in a model of multiple logistic regression. Results: We included 193 inpatients with TBC; 14 were HTLV-I positive (7.3%). In the multivariable analysis, HTLV-I infection (adjusted OR 9.4; CI 2.2 - 40.6), TBC meningitis (adjusted OR 3.8; CI 1.3 - 11.5) and unknown HIV infection status (adjusted OR 0.2; CI 0.04 - 0.6) were associated with death during hospitalization. Conclusions: HTLV-I is a frequent infection among inpatients with TBC and there is an independent association between HTLV-I infection and mortality among inpatients with TBC. (Rev Med Hered 2004;15:197-202).

Keywords : Human T-cell lymphotropic virus type I (HTLV-I); tuberculosis; mortality; Peru.

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