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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X

Abstract

CHUQUIYAURI HARO, Raul et al. Morbidity and mortality of patients with tuberculosis hospitalized at the Tropical Medicine, Infectious Diseases and Dermatology Department at the Hospital Nacional Cayetano Heredia from Lima-Peru, between 1990 - 2000. Rev Med Hered [online]. 2004, vol.15, n.4, pp.203-210. ISSN 1018-130X.

Objectives: To describe clinical and epidemiological characteristics and mortality of inpatients with tuberculosis (TB) at a department of infectious diseases of a public hospital in Peru. Material and methods: We conducted a retrospective and observational study and included patients with a definite or probable diagnosis of TB hospitalized at the Department of Infectious Diseases of the Hospital Nacional Cayetano Heredia (DEITD-HNCH) in Lima between January 1990 and December 2000. Results: There were registered 1340 admissions of patients with TB (18.7 %). The mean age of inpatients with TB was 33.5 ± 15.1 years; 69.2 % were men and 28.1% of TB patients were known to be infected with HIV. Mortality among TB patients was 17.2 % and kept constant during the period. Death because of TB (230 patients) represented 37.5 % of all death causes (613 patients). Among patients who died during the admission for TB, 151 (65.6 %) had multisystemic TB, 60 (26.1 %) had pulmonary TB and 19 (8.3 %) had extrapulmonary TB exclusively. There was clinical suspicion of multidrug-resistant TB (MDR-TB) in 51 (22.2 %) of the deceased patients. On multivariate analysis, being older than 30 years (OR=1.6, IC 95% 1.2-2.1) and having HIV infection (OR=5.4, IC 95% 4.0-7.3) were associated with mortality. Conclusions: TB represented 18.7% from the whole diagnostics and 37.5% from the whole deaths. The mortality related to TB in a unit of infectious diseases of a public reference hospital has not decreased over the last 11 years. Age over 30 years and being HIV infected were independently associated with death during hospitalization for TB. (Rev Med Hered 2004; 15:203-210).

Keywords : Tuberculosis; hospitalization; mortality; Perú.

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