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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X


BRENA CHAVEZ, Judith Patricia et al. Acute Bartonellosis in children. Study of 32 cases at the Instituto Especializado de Salud del Niño and the Hospital Nacional Cayetano Heredia (Period 1993-2003).. Rev Med Hered [online]. 2006, vol.17, n.3, pp.122-131. ISSN 1018-130X.

Objective: To determine the epidemiology, clinical presentation, data of laboratory and treatment of Bartonellosis in children. Material and methods: We evaluated clinical histories of 32 patients with acute Bartonellosis, who were seen at Instituto Especializado de Salud del Niño and the Hospital Nacional Cayetano Heredia from 1993 to 2003. Results: The mean age was 9.8 years, 72% of patients were men, the exposure geographic areas were mainly in endemic river valley of the Andes Mountain of Peru but there were nonendemic zones in the high forest; natives were 72%. The main symptoms were fever (97%), hiporexia (91%), gastrointestinal symptoms (66%) and malaise (53%). Common signs were pallor (97%), hepatomegaly (78%), tachycardia (75%) and lymphadenomegaly (72%). The mean hematocrit was 18,8%, severe anemia in 63%, leukocitosis in 63%, unconjugated hyperbilirrubinemia in 45% and hypoalbuminemia in 68%. Complications were frequent (78%), infectious in 25%, noninfectious in 22%, infectious and noninfectious in 31%. Infectious complications include respiratory (25%), typhoid fever / salmonellosis (19%), a case of infectious endocarditis. Among the noninfectious complications the most frequent were cardiovascular (34%) and neurologic complications (34%), there was a case of autoimmune hemolytic anemia; 72% received blood transfusion, 97% received antibiotic therapy, using chloramphenicol (56%), and ciprofloxacin (34%) The lethality was 6%. Conclusions: The Bartonellosis in this series was of great morbidity, the most frequent complications were cardiovascular, neurological and respiratory. (Rev Med Hered 2006;17:122-131).

Keywords : Bartonellosis; Carrión’s Disease; children.

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