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Revista Medica Herediana

versão impressa ISSN 1018-130Xversão On-line ISSN 1729-214X

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BRENA CHAVEZ, Judith Patricia et al. Acute Bartonellosis in children. Study of 32 cases at the Instituto Especializado de Salud del Niño and the Hospital Nacional Cayetano Heredia (Period 1993-2003).. Rev Med Hered [online]. 2006, vol.17, n.3, pp.122-131. ISSN 1018-130X.

Objective: To determine the epidemiology, clinical presentation, data of laboratory and treatment of Bartonellosis in children. Material and methods: We evaluated clinical histories of 32 patients with acute Bartonellosis, who were seen at Instituto Especializado de Salud del Niño and the Hospital Nacional Cayetano Heredia from 1993 to 2003. Results: The mean age was 9.8 years, 72% of patients were men, the exposure geographic areas were mainly in endemic river valley of the Andes Mountain of Peru but there were nonendemic zones in the high forest; natives were 72%. The main symptoms were fever (97%), hiporexia (91%), gastrointestinal symptoms (66%) and malaise (53%). Common signs were pallor (97%), hepatomegaly (78%), tachycardia (75%) and lymphadenomegaly (72%). The mean hematocrit was 18,8%, severe anemia in 63%, leukocitosis in 63%, unconjugated hyperbilirrubinemia in 45% and hypoalbuminemia in 68%. Complications were frequent (78%), infectious in 25%, noninfectious in 22%, infectious and noninfectious in 31%. Infectious complications include respiratory (25%), typhoid fever / salmonellosis (19%), a case of infectious endocarditis. Among the noninfectious complications the most frequent were cardiovascular (34%) and neurologic complications (34%), there was a case of autoimmune hemolytic anemia; 72% received blood transfusion, 97% received antibiotic therapy, using chloramphenicol (56%), and ciprofloxacin (34%) The lethality was 6%. Conclusions: The Bartonellosis in this series was of great morbidity, the most frequent complications were cardiovascular, neurological and respiratory. (Rev Med Hered 2006;17:122-131).

Palavras-chave : Bartonellosis; Carrión’s Disease; children.

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