SciELO - Scientific Electronic Library Online

 
vol.17 issue3Acute Bartonellosis in children. Study of 32 cases at the Instituto Especializado de Salud del Niño and the Hospital Nacional Cayetano Heredia (Period 1993-2003).Mortality among newborns with extreme low body weight at birth from the neonatology unit at the Hospital Nacional Cayetano Heredia author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X

Abstract

DELGADO ROSPIGLIOSI, Juan Luis; SECLEN SANTISTEBAN, Segundo Nicolás  and  GOTUZZO HERENCIA, Eduardo. Tuberculosis in diabetic patients: An epidemiologic and clinical study at the Hospital Nacional Cayetano Heredia. . Rev Med Hered [online]. 2006, vol.17, n.3, pp.132-140. ISSN 1018-130X.

Objectives: To describe epidemiological and clinical characteristics of diabetic patients with tuberculosis at the Hospital Nacional Cayetano Heredia (HNCH). Material and methods: Retrospective, observational, descriptive study. Diabetes Mellitus (DM) patients with Tuberculosis (TB) were found by searching the register books of the Endocrinology Service, Medicine in-patients Unit and Infectious and Tropical Diseases Department at the HNCH between 1997-2003. Results: There were 85 episodes on TB in 74 analyzed charts. The mean age was 49.4 + 12.8 years; 65% males, 35% females. 72/74 (97.3%) patients had type 2 DM. Patients were diagnosed with DM a mean of 4.2 +4 years prior to development of TB. 75/85 (88.2%) cases presented with pulmonary TB, of whom 51.3% were diagnosed by positive sputum smear. 59/85 (69%) cases were not regularly compliant with the treatment for DM and 60/85 (71%) had poor metabolic control when they developed TB. 31/74 (42%) patients were hospitalized because of TB. 51.4% of the hospitalizations were associated with diabetic ketoacidosis (DKA). TB can be a leading cause of DKA in our patients. The rate of treatment failures was 15/85 (17.6%); there was suspicion of MDR-TB in 13/74 (17.6%) patients. The rate of relapses was 15/74 (20.3%). 3/74 (4%) patients died during the period of study. Conclusions: Diabetic patients with poor metabolic control and TB frequently develop relapses, treatment failures and MDR-TB, raising significant concerns about nosocomial transmission. (Rev Med Hered 2006;17:132-140)

Keywords : Tuberculosis; diabetes mellitus.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )