Revista Medica Herediana
versión On-line ISSN 1729-214X
We report a 14-year-old girl with history of diabetes, obesity and, dyslipidemia. The patient was referred to our service because of polydipsia, polyuria and, overweight. Both parents were patients with type 2 diabetes. Physical examination showed abdominal obesity and severe acanthosis nigricans in skin folds. Laboratory results showed hyperglycemia, hyperinsulinemia, normal C-peptide and, the autoantibodies against islet antigens were negative. Treatment with metformin was continued. Diet and physical activity were reinforced. Currently, hemoglobin A1c and fasting plasma glucose have been improved.The rise in childhood obesity has resulted in a marked increase in the incidence of metabolic syndrome and type 2 diabetes in pediatric population.(Rev Med Hered 2010;21:103-106).
Palabras llave : Type 2 diabetes; obesity; insulin resistance; children; acanthosis nigricans; metabolic syndrome.