Abstract

MORI, Ricardo et al. Human T cell Lymphotropic Virus type 1 (HTLV-1) seroprevalence among out-patients with autoimmune thyroiditis. Rev Med Hered [online]. 2010, vol.21, n.4, pp.180-186. ISSN 1018-130X.

Objective: To describe the seroprevalence of human T-cell lymphotropic virus type 1 (HTLV-1) infection among patients with autoimmune thyroiditis diagnosis. Material and Methods: Cross-sectional study including subjects with autoimmune thyroiditis at the outpatient Endocrinology unit of the Hospital Nacional Cayetano Heredia from October 2008 to January 2010. A structured questionnaire was used to get epidemiologic and clinic data; and hospital registries were reviewed to determine laboratory data. Participants were tested for HTLV-1 using Enzyme-Linked Immunosorbent Assay and Western blot confirmation. All participant provided informed consent. Results: During the study period, 285 subjects with autoimmune thyroiditis were attended at the Endocrinology Outpatient Service. We included 145 (50.9%); their mean age was 48,1±15 years and 135 (93.1%) were female. Three were HTLV-1 positive, with estimated prevalence of 2.1% (95% CI: 0-4.4%). All seropositive patients were women and had Grave‘s disease. The frequency of HTLV-1 infection in this group was 5% (3/60); 95% CI: 0-11%. Non  significant differences for demographic, clinical and laboratory characteristics between the HTLV-1 seropositive and seronegative patients were founded. Conclusions: The seroprevalence of HTLV-1 infection among outpatients with autoimmune thyroiditis was similar to that estimated for the peruvian general population.(Rev Med Hered 2010;21:180-186)

Keywords : Autoimmune thyroiditis; Graves disease; Hashimoto thyroiditis; human T-cell lymphotropic virus type 1 (HTLV-1); prevalence.

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