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Revista Medica Herediana

Print version ISSN 1018-130X


MANRIQUE-HURTADO, Helard; PINTO-VALDIVIA, Miguel  and  ACOSTA-CHACALTANA, Max. Graves’ disease and thyroid cancer: A case report. Rev Med Hered [online]. 2011, vol.22, n.1, pp.34-37. ISSN 1018-130X.

We report the case a 62-year-old woman with recent history of hyperthyroidism due to Graves’ disease. Her medical history included treated rectal cancer. Physical exam showed a diffuse goiter with a nodule in the right thyroid lobe. Her thyroid profile was suppressed TSH and elevated thyroid hormones. Thyroid ultrasound confirmed a solid nodule in the right lobe, and thyroid scan showed increased uptake throughout the gland with a cold nodule in the lower level of right lobe. Histopatology study after thyroidectomy showed a moderately differentiated papillary thyroid cancer with local invasion and lymph node metastasis. Thyroid cancer with Graves’ disease has been reported in up to 9% of patients. In these cases, thyroid cancer is more aggressive as compared with those arising in patients with non-autoimmune hyperthyroidism or in euthyroid patients. Therefore, we suggest that patients with Graves’ disease should undergo an accurate examination of the thyroid gland not only by palpation but also by ultrasound. (Rev Med Hered 2011;22:34-37).

Keywords : Graves’ disease; hyperthyroidism; thyroid nodules; thyroid cancer.

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