Abstract

AZANA, Daisy; EGOAVIL, Miguel; SOTO, Leslie  and  DE LOS RIOS, Raul. Sensitivity of the gastric biopsy in detecting Helicobacter pylori infection in patients treated with proton pump inhibitors. Rev Med Hered [online]. 2012, vol.23, n.1, pp.11-15. ISSN 1018-130X.

Objective: To evaluate the sensitivity of gastric biopsy in detecting Helycobacter pylori (Hp) infection among patients who received proton pump inhibitors (PPI) 7-14 days before endoscopy compared to those who did not received PPI or who received a different medication. Methods: Case series. Patients with dyspepsia who undergo upper endoscopy and biopsy from November 2008 to January 2009 were included if they had received PPI 7-14 days before the procedure. Patients with gastric cancer, prior surgery and those who had received antibiotics or bismuth subsalicylate were excluded. Two biopsies of the main gastric body and antrum were taken. The STATA software was used for the analysis. Results: 80 patients were studied; 38 (47.5%) received PPI. 64.29% (27/42) of those who did not received PPI were Hp positive vs. 65.79% (23/38) in patients who received PPIs (p=0.90). Conclusions: Hp rate was similar irrespective of PPI use.

Keywords : Helicobacter pylori; antacids; dyspepsia; endoscopy; biopsy.

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