Abstract

SALINAS ARCE, Jorge Luis; PINTO VALDIVIA, Miguel  and  SOLORZANO ALTAMIRANO, Paula. Amiodarone-induced hypothyroidism: Case report. Rev Med Hered [online]. 2012, vol.23, n.1, pp.45-47. ISSN 1018-130X.

We report a case of a Wolf Parkinson White syndrome in a 57-yearl-old woman receiving amiodarone (200 mg/ day) who presented with tachycardia, fatigue and somnolence. The physical examination did not reveal goiter, but the osteotendinous reflexes were brisk. Laboratory examinations revealed high TSH level, low T4 free level and negative antiperoxidase antibodies. Amiodarone was stopped and levotiroxine was started. Two months after, TSH and T4 free levels were normal and the patient was asymptomatic. Amiodarone is associated with several side effects that can preclude its indication; one of these side effects is hypothiroidism, characterized by high TSH levels, low T4 free levels and unspecific symptoms such as fatigue, cool intolerance and dry skin. The treatment of choice is levotiroxine

Keywords : Amiodarone; hypothyroidism; thyroiditis.

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