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Revista Medica Herediana
Print version ISSN 1018-130X
Abstract
LOZA-MUNARRIZ, Reyner et al. Membranous Nephropathy secondary to Cytomegalovirus infection: A case report. Rev Med Hered [online]. 2012, vol.23, n.4, pp.251-255. ISSN 1018-130X.
The most frequent causes of nephrotic syndrome in children are minimal change glomerulopathy and focalsegmental glomeruloesclerosis, secondary forms are less frequent. We present the case of 5-year and 7-month boy with nephrotic syndrome resistant to steroids in whom the renal biopsy showed membranous glomerulonephritis with focal cythopatic changes in the tubular cells compatible with cytomegalovirus infection. Immunofluorescence showed mesangial deposits of IgM and C3. Proteinuria remitted with intravenous gancyclovir therapy followed by oral valgancyclovir and cyclophosphamide.
Keywords : Nephrotic syndrome; child; cytomegalovirus; membranous glomerulonephritis.