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Revista Medica Herediana

Print version ISSN 1018-130X


PINTO, Miguel et al. Doege-Potter Syndrome: A case report. Rev Med Hered [online]. 2013, vol.24, n.2, pp.136-140. ISSN 1018-130X.

The solitary fibrous tumor of the pleura is an infrequent neoplasm. Hypoglycemia is a paraneoplastic manifestation of this tumor and it is named the Doege-Potter Syndrome. Hypoglycemia results from the aberrant tumoral secretion of IGF-II that permanently stimulates the insulin receptor. Surgical removal of the tumor is the treatment of choice and results in immediate resolution of hypoglycemia with low risk of recurrence. We present the case of a 55-year-old female patient who attended the emergency room with recurrent episodes of hypoglycemia. On admission, the laboratory results revealed severe hypoglycemia and low levels of insulin and C-peptide. Chest x-ray showed a homogenous opacity that affected almost the entire right hemithorax. The CT-scan showed a heterogeneous tumor with no well-defined borders. An open thoracotomy with complete resection of the tumor was performed. Histopathological findings were compatible with solitary fibrous tumor of the pleura. Hypoglycemic episodes resolved and the patient was discharged.

Keywords : Hypoglycemia; solitary fibrous tumor; pleural; paraneoplastic syndromes.

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