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Revista Medica Herediana

On-line version ISSN 1729-214X


VERA, Luis; BAUTISTA, Fernando; CASTANEDA, Enrique  and  ARBOLEDA, Miguel. Surgical treatment of great arteries transposition and risk factors for mortality. Rev Med Hered [online]. 2013, vol.24, n.3, pp.192-198. ISSN 1729-214X.

Great arteries transposition is a discordant atrioventricular connection whose incidence varies between 0.02% to 0.05% of all newborns and represents 5-8% of all congenital cardiopathies. The tratment of choice for this condition is the Jatene´s surgical procedure. Objectives: To describe clinical features of patients with great arteries transposition in whom Jatene´s procedure was performed and to explore risk factors for mortality among them. Methods: A retrospective and descriptive study was conducted between January 2001 and December 2010. A database in SPSS v19.0 was created. Results: 52 patients were analyzed; 77% were male; mean body weight was 3500 g; mean age was 54.83 days. Most of the cases presented with artery transposition with intact interventricular septum and with normal coronary arterial distribution. Overall in-hospital mortality was 31%, which was reduced to 16% in the last 3-year period. Age above 23 days was associated with six times more mortality. Conclusions: Our findings are in agreement with previous international reports. Age above 23 days was a risk factor for mortality, which was reduced to 16% in the last 3 years of the study period. Additional measures need to be undertaken to further reduce the high mortality observed.

Keywords : Transposition of great vessels; heart defects; congenital.

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