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Revista Medica Herediana

On-line version ISSN 1729-214X


POLANCO HINOSTROZA, Fernando  and  LOZA MUNARRIZ, Reyner. Antibiotic resistance of pathogens causing urinary tract infections in children attended at a private institution from 2007-2011. Rev Med Hered [online]. 2013, vol.24, n.3, pp.210-216. ISSN 1729-214X.

Antibiotic resistance is a major public health concern among patients with urinary tract infections (UTI), particularly among those with recurrent infections and in those with urinary tract anomalies. Objective: Describe the antimicrobial resistant pattern of bacterial pathogens causing UTI including fist episodes, recurrent episodes and complicated UTIs in children below 5 years of age. Methods: Retrospective case-series over a 5-year period that included patients with confirmed UTI whose charts were reviewed to extract relevant data. Results: A total of 111 children were included from 1 month to 5 years of age; 97 (87,4%) were females; 68 (61,3%) were breastfed; 77% had UTI; 34 had recurrent or complicated UTI. Escherichia coli (63,1%) was the most common pathogen in all age groups, and the antibiotic resistance profile was as follows: 80,6% to ampicillin, 59% to cefalotine, 55,4% to amoxicillin-clavunaic acid, 51,6% to trimethoprim-sulfamethoxazol, 51% to nalidix acid, 40% to cephalexin, 31% to cefotaxime, 29,8% to cefuroxime, 28,6% to ceftriaxone, 27,3% to ceftazidime, 21,2% to norfloxacin, 21,1% to ciprofloxacin, 17% to nitrofurantoin, 13,2% to gentamycin and 1% to amikacin. Conclusions: There is a high antibiotic resistance profile to most of the common antimicrobials used to treat UTIs. Aminolgycosides are the first choice based on their antibiotic resistant profile.

Keywords : Drug resistance; Anti-bacterial agents.

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