Abstract

TAFUR, Karla; CACERES, Jaime  and  ACCINELLI, Roberto. Características clínicas y anatomo-patológicas de las pacientes que ingresaron al Programa de Control de Tuberculosis con diagnóstico de tuberculosis de mama: Clinical and pathological features of patients treated at the tuberculosis control program with the diagnosis of breast tuberculosis. Rev Med Hered [online]. 2014, vol.25, n.4, pp.215-222. ISSN 1018-130X.

Objective: To describe clinical and pathological features of patients treated at the tuberculosis (TB) control program (TCP) with the diagnosis of breast TB in a general hospital. Methods: Patients registered at the TCP with the pathological diagnosis of chronic granulomatous mastitis were included. Clinical and pathological slides were reviewed. Results: A total of 69 women were included; mean age was 35.79 ± 7.94 years of age. The most common clinical manifestations were a nodular lesion (89.96%), pain (89.96%) and inflammatory signs (4058%). Reevaluation of biopsies showed suppurated granulomas with Langhans´ multinucleated giant cells without caseuous necrosis located at the duct-lobular (DL) and extra DL areas in 85.1% of cases. Acid-fast bacilli were seen in only 3 cases. All cases received anti TB treatment. Thirty-eight patients had follow-up, 73.68% of them had recurrence or persistence at least one month after starting anti TB treatment. Conclusions: Nodular lesions with pain and inflammatory signs in absence of systemic symptoms, and suppurated granulomas without caseuous necrosis were the most frequent findings. Despite receiving anti TB treatment, almost 75% of patients with follow-up had persistence or clinical recurrence.

Keywords : Tuberculosis; granulomatous mastitis; pathology.

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