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Revista Medica Herediana

Print version ISSN 1018-130X


MENDOZA DEL SOLAR, Gonzalo; ECHEGARAY, Anuska  and  CASO, Cesar. Immunohistochemistry profile of breast cancer in a general hospital in Arequipa, Peru. Rev Med Hered [online]. 2015, vol.26, n.1, pp.31-34. ISSN 1018-130X.

Immunohistochemistry results allow for a personalized treatment of patients with breast cancer. Objective: To determine the immunohistochemistry profile of patients with breast cancer in a general hospital in Arequipa, Peru. Methods: Retrospective study carried out at Hospital Goyeneche from January 2007 to December 2012. Hormonal receptor studies and Cerb-2 immunohistochemistry panels were performed. Results: 50,8% of cases had RE, 44,6% had RP and 23,1% had Cerb-2; 30,8% of breast cancers had all three negative markers. Conclusions: The immunohistochemistry profile of this setting is similar than reported elsewhere. More than half of patients had positive estrogenic receptors and were amenable of hormonal manipulation; one fifth of cases were Cerb-2 positive amenable of treatment with monoclonal antibodies and one third had negative markers are therefore poor prognosis

Keywords : Breast neoplasms; biological markers; immunohistochemistry.

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