Abstract

GUEVARA-LINARES, Ximena; JASSO-HUAMAN, Luis; RAMIREZ-VELA, Rosa María  and  PINTO-VALDIVIA, Miguel. Clinical and demographic features andthyroid hormone profile in hospitalized patients with hyperthyroidism in a general hospital. Rev Med Hered [online]. 2015, vol.26, n.3, pp.141-146. ISSN 1018-130X.

Objective: To describe the clinical features and causes of hospitalization in patients with hyperthyroidism in a general hospitalin Lima, Peru. Methods: A retrospective and descriptive study wascarried out. The study population was all patients hospitalized with thediagnosis of hyperthyroidism from January 1989 to December 2005 at Hospital Nacional Cayetano Heredia. Sourcedata was the consultation book-record of the Endocrinology service. Clinical and demographic features were gathered. Results: 230 patientswere identified, 162 clinical charts were reviewed. Median age was 36 years ofage; 79% of patients were female, and Graves disease (GD) was the most common cause of hyperthyroidism (87.65%), followed by nodular thyroid disease (NTD, 12.35%). Patients with GD were younger and hadbeen borne in the coast, while patients with NTD were older and had been bornin the highlands. The most common reasons for hospitalization were cardiovascular involvement (heart failure and atrial fibrillation), infectionsand gyneco-obstetric complications. Most of thepatients were treated with thioamides and beta-blockers. Mortality was 1.2%. Conclusions: As reported in other national studies the most common cause for hospitalization was GD with cardiovascular involvement. Mortality was lower than previously reported.

Keywords : Hyperthyroidism; Graves’disease; epidemiology.

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