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Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X

Abstract

CALLE NUNEZ, Adriana; COLQUI CAMPOS, Kevin Antonio; RIVERA ESTRELLA, David Alonso  and  CIEZA ZEVALLOS, Javier Antonio. Factors associated with urinary tract infections caused by extended spectrum betalactamase producing strains of Escherichia coli. Rev Med Hered [online]. 2017, vol.28, n.3, pp.142-149. ISSN 1018-130X.  http://dx.doi.org/https://doi.org/10.20453/rmh.v28i3.3180.

Objectives: To determine factors associated with urinary tract infections caused by extended spectrum betalactamase producing strains (ESBL) of Escherichia coli. Methods: Case-control study performed at Hospital Cayetano Heredia; 150 cases (patients with positive urine cultures for an ESBL producing strain of E. coli) and 150 controls (patients with positive urine culture to a non-ESBL producing strain of E. coli) were included. Bivariate and multivariate logistic regression analysis were performed. Results: Factors associated with having an infection by an ESBL producing strain of E. coli in the multivariate analysis were male sex (OR 5.13 - CI 95% 2.37 - 11.07), age above 45 years (OR 2.65 - CI 95% 1.61 - 4.38) and previous hospitalization (OR 2.57 - CI 95% 1.39-4.75). Conclusions: Empirical treatment for ESBL producing strains of E. coli should be targeted to male patients older than 45 years of age, and in those with a previous hospitalization.

Keywords : Urinary tract; beta-Lactamases; Escherichia coli; antibiotic resistance; drug resistance bacterial.

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