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Revista Medica Herediana
Print version ISSN 1018-130XOn-line version ISSN 1729-214X
Abstract
JARAMILLO-ORDONEZ, Cristhina Estefanía. In-vitro antifungal and antibacterial activity of the ethanolic extract of Usnea laevis against Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa. Rev Med Hered [online]. 2020, vol.31, n.3, pp.169-174. ISSN 1018-130X. http://dx.doi.org/10.20453/rmh.v31i3.3806.
Lichens are symbiotic associations between fungi and seaweed or cyanobacteria.
Objective:
to evaluate the in-vitro antifungal and antibacterial activity of the ethanolic extract of Usnea laevis against Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa.
Methods:
lichened substances present in Usnea laevis were extracted using the Soxhlet methods and were analyzed by chromatography coupled to mass spectrometry. The Kirby-Bauer method was used to evaluate both the antibacterial and antifungal activity.
Results:
Usnic acid, eugenol, and ergosterol were the compounds found. S. aureus was sensitive at a concentration of 27 mg/ml of the enolic extract, the 11 mg/ml concentration was not effective.
Conclusions:
The ethanolic extract of Usnea laevis has antibacterial and antifungal properties against the pathogens tested.
Keywords : Usnea; antifungal agents; anti-bacterial agents; plant extracts.