SciELO - Scientific Electronic Library Online

vol.33 issue2External lesions and their relationship with alcohol consumption in patients attending in an emergency hospital in Lima, Peru author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Medica Herediana

Print version ISSN 1018-130XOn-line version ISSN 1729-214X


ZEGARRA PIEROLA, Jaime; FERNANDEZ MERJILDO, Diana; LEVANO DIAZ, Lady  and  TICONA SALAZAR, José. Mechanical ventilation in patients with acute respiratory distress syndrome due to Covid-19 in an intensive care unit in Lima, Peru. Rev Med Hered [online]. 2022, vol.33, n.2, pp.81-90.  Epub July 06, 2022. ISSN 1018-130X.


To describe clinical, epidemiological, mechanical ventilation (MV) parameters and to determine overall mortality and that related to MV parameters in patients with acute respiratory distress syndrome (ARDS) in an ICU in Lima, Peru.


A retrospective cohort including 133 patients with ARDS due to Covid-19 requiring MV in the Hospital Cayetano Heredia’s ICU was built from March to November 2020.


Males accounted for 75% of the cohort; 68% had no comorbidities; 97% has severe ARDS and 82% received extended 72h prone MV. Overall mortality was 38%; bivariate analysis found that alive patients had lower plateau pressure 27±1 cm H20 vs. 30±1 cm H20 (p=0.007), lower driving pressure 15±4 vs. 17±5 (p=0.008), higher static lung compliance 32±1 vs. 28±1 ml/cm H20 (p=0.01) and higher Pa02/Fi02 ratio 194±86 mm Hg vs. 157±66 mm Hg (p=0.01) than patients who died. Patients on extended prone MV had better survival (p=0.03).


97% of patients in the cohort had severe ARDS; overall mortality was 38%, alive patients had lower plateau pressure and less driving pressure and extended prone MV improved survival.

Keywords : Mechanical ventilation; acute respiratory distress syndrome; coronavirus infections.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )