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Revista Estomatológica Herediana
Print version ISSN 1019-4355
Abstract
GUTIERREZ PATINO-PAUL, Alejandro and RIVADENEYRA RODRIGUEZ, Abel. Recurrent odontogenic keratocyst in patient with Gorlin-Goltz Syndrome. Rev. Estomatol. Herediana [online]. 2020, vol.30, n.1, pp.53-62. ISSN 1019-4355. http://dx.doi.org/10.20453/reh.v30i1.3741.
Gorlin-Goltz syndrome (GGS) is an autosomal dominant disorder characterized by skeletal abnormalities, multi-ple Keratocysts Odontogenic (KCOs) and basal cell carcinoma. Comparative studies of the associated KCOs and those not associated with the GGS have been performed, and the presence of a greater number of satellite cysts, solid proliferations of the epithelium, inflammations, calcifications, more intense mitotic activity of the epithelial cells, and greater recurrence of the KCOs associated with the GGS. The purpose of this case report is to provide an objective basis for the therapeutic management of KCOs in patients with GGS and a review of the scientifi c literature. We present the case of a 63-year-old patient, with a history of GGS, who underwent multiple surgical interventions, including exeresis of KCOs in both jaws, who came to the consultation, nine years after her last intervention, for an Odontostomatological check-up, finding KCO recurrent in upper right maxilla, performing enucleation, peripheral ostectomy and application of carnoy solution.
Keywords : Odontogenic Keratocyst; Gorlin-Goltz Syndrome; Patched Gene..