Abstract

GUTIERREZ PATINO-PAUL, Alejandro Arturo. An unusual case of multiple oral pyogenic granuloma, ¿associated with treatment with levothyroxin?. Rev. Estomatol. Herediana [online]. 2020, vol.30, n.4, pp.294-301. ISSN 1019-4355.  http://dx.doi.org/10.20453/reh.v30i4.3883.

Pyogenic Granuloma (GP) is a tumorous, non-neoplastic, vascular, generally solitary lesion that presents itself in the oral cavity or skin, the etiology is still not very clear, it is considered to be a reactive lesion to several low grade stimuli, among which we can count repeated trauma, aggressions, hormonal factors and certain drugs. The multiple GP, is a rare phenomenon, generally associated with the use of drugs, such as carbamacepine, cyclosporine, retinoids, levothyroxine, etc. It presents the case of a patient of 50 years, referred for presenting increased volume in alveolar ridge of the first, third and fourth quadrants, with a history of erythrodermic psoriasis and hypothyroidism, in treatment with levothyroxine approximately six months before the lesions occur; Surgical exeresis and subperiosteal curettage is performed, samples were sent to pathological anatomy, confirming the definitive diagnosis of GP; because of the history, and the almost simultaneous appearance of the lesions in multiple quadrants, it is suspected that these are associated with the therapeutic consumption of levothyroxine for hypothyroidism.

Keywords : Pyogenic granuloma; hypothyroidism; levothyroxine.

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