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Revista de Gastroenterología del Perú

Print version ISSN 1022-5129


LOPEZ DE GUIMARAES, Douglas; NEYRA LLANOS, Rosario Soledad  and  ROMERO ACEVEDO, Juan Hugo. Ascaridiasis: comparación de la eficacia terapeutica entre paico y albendazol en niños de Huaraz. Rev. gastroenterol. Perú [online]. 2001, vol.21, n.3, pp.212-219. ISSN 1022-5129.

A therapeutical clinical trial was designed to study the effectiveness of Paico and Albendazole, for the treatment of ascaridiasis in a group of 60 children, between 3 and 14 years old, from a rural community in Huaraz. It was carried out between May and August, 2000. The sample was randomly divided into 30 cases for Paico and 30 for Albendazole, the criteria for entering the trial being a positive examination for Ascaris lumbricoides in feces. The treatment consisted in Paico juice: 1 ml/Kg for less than 10 Kg, and 2 mllKg in larger children, one dose before breakfast, for three consecutive days. The Albendazole was administered in a single dóse of 400 mg in those over five years of age, and 200 mg in younger children. The effectiveness was evaluated qualitatively (the disappearance of the ascaris eggs from the feces) and quantitatively (decrease in the parasitic burden); in the stool examinations carried out in all cases on entering the study and 15 days after the treatment. All the stool samples were processed in the Referential Laboratory of the Regional Health Authority in Ancash. The qualitative effectiveness between Paico and Albendazole for the eradication of ascaridiasis was similar at 86.7%. The quantitative effectiveness was 59.5% for Paico and 58.3% for Albendazole. However, it was observed that, unlike Albedazole, Paico is 100% effective in the treatment of Hymenolepsis nana. Adverse effects were presented in 23.3% of the cases for both drugs. It is concluded that, although Paico and Albendazole have a similar effectiveness against Ascaris lumbricoides, Paico has the additional benefit of being effective against Hymenolepsis nana.

Keywords : Intestinal parasitosis; Paico; Albendazole.

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