Resumen

MORISHITA, Tetsuo, NAKAYAMA, Takamori, KAMIYA, Toshiaki et al. Basic and Clinical Aspects of Clostridium Difficile Colitis. Rev. gastroenterol. Perú, jul./set. 2004, vol.24, no.3, p.263-269. ISSN 1022-5129.

Clostridium difficile, a gram-positive anaerobic bacillus dubbed as the difficult clostridium because it resisted early attempts of isolation and cultura. After some decades in the dakness, it became famous, when in 1978, a cytotoxin of the C. difficile was found the responsable of the pseudomembranous colitis. We review in this paper aspects of the epidemiology of the C. difficile in health and disease. Also the importance of C. difficile as a cause of nosocomial infections. We review the caracheristics of the toxins A and B produced by the pathogenics strains of C. difficile. Finally, clinical aspects of infection with C. difficile in special in the pseudomembranosa colitis. The diagnosis, medical therapy, complications and surgical indications are briefly described.

Palabras llave: Clostridium difficille; Pseudomembranosa colitis.