Abstract

BASTO VALENCIA, Milagros; VARGAS CARDENAS, Gloria  and  ANGELES CHAPARRO, Pabel. Factores de riesgo que incrementan la Morbimortalidad en Pacientes con Hemorragia Digestiva Alta en el Hospital Nacional "Arzobispo Loayza" 1980-2003. Rev. gastroenterol. Perú [online]. 2005, vol.25, n.3, pp.259-267. ISSN 1022-5129.

Upper gastrointestinal bleeding is a digestive disorder with both high morbility and mortality, being the most important digestive emergency. The objective of study was to find risk factors than increase morbimortality and efficacy treatment of used. Materials and methods: The design was is a retrospective case- control study, an alleatory unrestrictive sample was done, with 104 subjects each group, selected by the alleatory numbers table. Results: Risk factors associated to mobility: major bleeding was male population (OR=1.94,CL 1.08 - 3.50), previous alcohol consume (OR = 2.47,CL 1.32-- 4.66); previous peptic ulcer (OR = 2.83,CL 1.16-- 7.07); chronic liver disease (OR = 4.55,CL 1.36-- 16.77); haematemesis and melaena (OR = 2.85,CL 1.53-- 5.34); and only haematemesis (OR = 3.40,CL 1.62 - 7.23); injury assigned as risk factor were esophagogastric varices(OR = 4.64,CL 1.96 - 13.42). Combinated treatments medical-endoscopic and medical-surgical treatments were determinate as protectors factors with RR=0,52 (CL 0.37 - 0.73) y RR= 0.09 (CL 0.01 - 0.61) respectably. Mortality: 0.40% Conclusion: Risk factors associated to morbi-mortality were: chronic liver desease, esophago-gastric varices, haematemesis and melaena. Treatment medical-endoscopic and medical-surgery are protective factors. Mortality: 0.48% can be attributed to improvement of endoscopic treatments and convenient surgery treatment considered as protector factors with high efficacy.

Keywords : Upper Gastrointestinal Bleeding; risk factors; mobility; mortality.

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