Abstract

TORRES ZAVALA, Neyda Milagros; YAN - QUIROZ, Edgar Fermín; DIAZ - PLASENCIA, Juan Alberto  and  BURGOS - CHAVEZ, Othoniel Abelardo. Prognostic Factors of Survival in Obstructive and Non-Obstructive Excisable Colorectal Cancer. Rev. gastroenterol. Perú [online]. 2006, vol.26, n.4, pp.363-372. ISSN 1022-5129.

OBJECTIVES: Determining the prognostic factors, clinical and pathological characteristics, surgical morbidity and mortality and actuarial survival after five (5) years of patients with obstructive and non-obstructive excisable colorectal cancer. MATERIAL AND METHODS: Descriptive, correlative, longitudinal and observational study at the Belen Hospital in Trujillo of 88 patients with excisable colorectal cancer and a histological confirmation of their disease, between 1966 and 2000. RESULTS: The mean age of the total series was 62.35 ± 14.64 years; the primary tumor (p = 0.001) and regional ganglionic condition (p = 0.0001) were the factors associated with the five year survival in both groups of patients with obstructive and non-obstructive colorectal cancer. Furthermore, the size of the tumors and distance metastasis were also prognostic factors associated in patients with non-obstructive colorectal cancer. Actuarial survival at 60 months of patients with obstructive and non-obstructive colorectal cancer who had surgery for curative purposes was 65.5% and 20%, respectively (p = 0.0135). The actuarial survival rate of patients with obstructive excisable colorectal cancer was 9.5% and in patients with non-obstructive colorectal cancer it was 35.1% (p = 0.1480). CONCLUSIONS: The primary tumor and regional ganglionic condition were prognostic factors in both groups. Furthermore, size of the tumors, distance metastasis and clinical stage were also prognostic factors in patients with non-obstructive colorectal cancer.

Keywords : Colorectal Cancer; Survival; Prognostic factors; Clinical; Pathology.

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