Resumen

BARISIO D´ANGELO, María Gabriela; MARIEL ACTIS, Andrea  y  OUTOMURO, Delia. Non alcoholic fatty liver: a frequent entity with an unknown outcome. Rev. gastroenterol. Perú [online]. 2009, vol.29, n.1, pp.44-50. ISSN 1022-5129.

Non-alcoholic fatty liver disease (NAFLD), defined as excessive fat accumulation into the hepatocytes, has a prevalence of approximately 15 to 25%. Frequently associated risk factors for NAFLD are obesity, type 2 diabetes and dyslipidemia. It has been proposed that a mitochondrial dysfunction would play a crucial role in the disease development. On the other hand, focus is on insulin resistance syndrome, the only metabolic alteration strongly associated with this malady. The disease is suspected in individuals with insulin resistance characteristics such as metabolic syndrome and also in those with augmented serum aminotransferases levels. Different tests with biochemical markers have been proposed to predict the development of fibrosis or steatohepatitis. Therapeutic options in NAFLD patients are limited and weight lost remains as the most recommended one.

Palabras clave : NAFLD; NASH; insulin resistance; Steato Test; Fibro Test.

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