SciELO - Scientific Electronic Library Online

vol.31 issue4Ciprofloxacin vs Cefazolin in the prevention of infection in Cirrhotic patients with Gastrointestional Bleeding author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista de Gastroenterología del Perú

Print version ISSN 1022-5129


AREVALO, F. et al. Increase of Intraepithelial Lymphocytes in patients with Irritable Bowel Syndrome. Rev. gastroenterol. Perú [online]. 2011, vol.31, n.4, pp.315-318. ISSN 1022-5129.

Several studies have shown increased numbers of intraepithelial lymphocytes (IEL), mast cells, enterochromaffin cells in colonic mucosa of patients with Irritable Bowel Syndrome (IBS). Many of these findings are based is based on immunohistochemistry results, which is not available in general hospitals. Our objective is to study the histological findings observed in colon biopsies from patients with IBS compared with a group without IBS, using only histochemistry. Twenty five (25) patients were included: 16 with IBS and 9 without IBS. We found increased numbers of IEL in patients with IBS (p=0,002). A group of patients with IBS (41.9%) who fulfilled histological criteria for lymphocytic colitis were excluded. There was no significant difference in mast cells, enterochromaffin cells or eosinophils.

Keywords : Irritable Bowel Syndrome; intraepithelial lymphocytes; mast cell; enterochromaffin cell.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )