Abstract

LABAN VILLANUEVA, Carlos Enrique; DIAZ PLASENCIA, Juan Alberto; YAN QUIROZ, Edgar Fermín  and  GUEVARA ARRASCUE, José Luis. Trends in incidence and risk factors associated with the development of pancreatic cancer: Regional Institute of Neoplastic Diseases "Dr. Luis Pinillos Ganoza"- IREN North. 2008 - 2011. Rev. gastroenterol. Perú [online]. 2012, vol.32, n.2, pp.161-168. ISSN 1022-5129.

OBJECTIVE. To determine trends in the prevalence and identify the main risk factors associated with the development of pancreatic cancer. MATERIALS AND METHODS. Study of trends in incidence and case-control population consisted of a total of 134 patients. Patients were grouped into: a) Cases: 67 patients diagnosed with pancreatic cancer treated at the Abdomen’s Service of the Specialized Surgery Department of the Regional Institute of Neoplastic Diseases "Dr. Luis Pinillos Ganoza "- IREN North during the period 2008 to 2011; and b) Controls: 67 patients diagnosed with gallstones and / or benign biliary disease treated at Belen Hospital in Trujillo during the period 2008 to 2011. RESULTS. The trend curve of incidence of pancreatic cancer showed a curve almost constant throughout the quadrennium 2008 to 2011, with incidence rates of 5.38%, 5.08%, 5.5% and 5.0% respectively. The overall incidence was 5.37%. The trend function was Y = (1756) ± (0.001) (x), with an R2 = 0.318 (p = 0.436). The main risk factors associated with pancreatic cancer were age bigger and equal to 60 years (p = 0.0001), male sex (p = 0.007), diabetes mellitus (p = 0.002) and family history of malignancy (p = 0.016) CONCLUSIONS. The trend in incidence in pancreatic cancer was low and constant in its appearance was significantly influenced by age, gender, and presence of diabetes mellitus and family history of cancer.

Keywords : Trends; Incidence; Risk factors; Pancreatic Cancer.

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