Revista de Gastroenterología del Perú
Print version ISSN 1022-5129
SOUTELO, María J. et al. Glycemic dysfunction prevalence post acute pancreatitis: A prospective study. Rev. gastroenterol. Perú [online]. 2012, vol.32, n.3, pp. 262-266. ISSN 1022-5129.
OBJECTIVE: To estimate the prevalence of altered metabolism of carbohydrates in patients with mild acute pancreatitis METHODS: We included 85 patients diagnosed with pancreatitis. We used to evaluate prognosis Balthazar and Ranson criteria. All patients were interviewed and examined. Was performed routine laboratory and Oral glucose tolerance test (OGTT) We excluded patients with previous diagnosis of diabetes mellitus, alcoholic pancreatitis, severe hypertriglyceridemia and recurrent/ severe pancreatitis RESULTS: 30 women and 27 men. After performing the OGTT were classified into three groups. Group 1 (n: 19): normal OGTT; Group 2 (n: 33): GAA, IHC, or both, and Group 3 (n = 5): with diabetes mellitus. Patients in group 3 had a higher average age (p = 0.02), and higher diastolic blood pressure (DBP) (p = 0.048). We observe a significant difference in fasting glucose values (p = 0.0001) and 120 minutes post-OGTT in all groups (p = 0.0001). HOMA was found higher (p = 0.031) in group 2. CONCLUSIONS: This study showing a link between mild acute pancreatitis and dysfunction of glucose metabolism, which found older patients, DBP and those with metabolic syndrome, had a higher prevalence of 65.66% of Pre diabetes and diabetes.
Keywords : Pancreatitis; Mild acute pancreatitis; Dysglycemia; Glucose metabolism disorders; Cause pancreatic diabetes.