Abstract

PAREDES MILLAN, Mileydy; CHIRINOS MONTES, Nataly Juliana; MARTINEZ APAZA, Anthony  and  LOZANO, Adelina. The most common rheumatic diseases in patients with autoimmune liver disease in the Hospital Arzobispo Loayza from 2008 -2013, Lima, Peru. Rev. gastroenterol. Perú [online]. 2014, vol.34, n.4, pp.305-310. ISSN 1022-5129.

Objective: To identify the most common autoimmune rheumatic diseases in patients with autoimmune liver disease in the Hospital Arzobispo Loayza (HAL) from 2008 -2013. Materials and methods: This is a transversal and descriptive study, we analyzed 125 medical records, only 86 patients fulfill the diagnostic criteria for autoimmune liver disease, of whom 46 had diagnosis of autoimmune hepatitis(AIH), 39 primary biliary cirrhosis(PBC) and just 1 primary sclerosing cholangitis (PSC). In our study group we looked for the clinical and laboratory characteristics most common and the frequency of cases in the HAL. Results: Of the 46 patients with AIH, 16 (34.78%) were diagnosed with autoimmune rheumatic disease concurrence. Of these, 7 (15.22%) patients had Sjogren´s Disease (SD), 6 (13.04%) had systemic lupus erythematosus (SLE) and 3 (6.52%) had rheumatoid arthritis (RA). We found 39 patients with PBC, 18 (46.15%) had other associated extrahepatic autoimmune disease, of whom 12 (30.77%) had SD, 3 (7.69%) SLE and 3 (7.69%) RA. One patient had the diagnosis of PSC, a sixty year old woman that had no concurrence with rheumatic disease. Conclusions: In our study was found that SD is the most common rheumatic disease in patients with AIH and PBC, followed by SLE and RA, this leads us to look for these diseases in patients with autoimmune liver disease with rheumatic symptoms and vice versa.

Keywords : Hepatitis, autoimmune; Liver cirrhosis, biliary; Rheumatology.

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