Abstract

MELO PEZO, Xavier; MEDRANO SAMAME, Hector  and  TORRES ROSAS, Eliana. Hereditary diffuse gastric cancer. Rev. gastroenterol. Perú [online]. 2015, vol.35, n.1, pp.63-71. ISSN 1022-5129.

Hereditary diffuse gastric cancer is an autosomal dominant syndrome associated to CDH1 gene mutation that affects at least 30% of CDH1+ families, with a penetrance of 80% at 80 years, and multifocal signed ring cell in most of the cases. The suggested treatment is a prophylactic total gastrectomy with Roux-en-Y esophagojejunostomy, but if this is rejected, it is necessary endoscopic surveillance and if there is a minimum malignancy sing must be imperative a gastrectomy

Keywords : Gastric cancer; Gastrectomy; Carcinoma; signet ring cell.

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