Abstract

MCDONALD, Katharine et al. Correlation between functional gastrointestinal disorders and gastric mucosa histopathology findings, including Helicobacter pylori infection, in Lima, Peru. Rev. gastroenterol. Perú [online]. 2015, vol.35, n.2, pp.137-140. ISSN 1022-5129.

Objective: This study aims to investigate the relationship between functional gastrointestinal disorders and histopathology characteristics, including H. pylori infection, of gastric mucosa, at Cayetano Heredia National Hospital, Lima-Peru, in 2013. Materials and methods: 112 patients were interviewed prospectively between June and July 2013 in the gastroenterology service. Dyspepsia, irritable bowel syndrome, and postprandial distress syndrome were characterized using the Rome III Survey. Results: Pathology results were determined by gastric biopsies obtained by endoscopy. Of the patients interviewed, biopsy results were obtained for 101. 22.8% had atrophy, 24.8% had intestinal metaplasia, 57.4% presented with H pylori. Conclusions: Using chi-square analysis, no statistically significant relationship could be identified between clinical presentation and biopsy results.

Keywords : Functional GI disorders; dyspepsia; irritable bowel syndrome; postprandial distress syndrome; gastric biopsy; Helicobacter pylori.

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