Abstract

AREVALO, Fernando et al. Neuroendocrine hiperplasia in linfocitic and ulcerative colitis. Rev. gastroenterol. Perú [online]. 2018, vol.38, n.4, pp.345-348. ISSN 1022-5129.

Introduction: Some authors have found increase of neuroendocrine cells in microscopic colitis and ulcerative colitis. Objective: The aim of this study is to evaluate the presence of neuroendocrine cells in ulcerative colitis and lymphocytic colitis and collagenous colitis. Materials and methods: Immunohistochemistry was performed to identify neuroendocrine cells through marker chromogranin A (CgA). The study included 10 cases of each diagnosis of Lymphocytic colitis, collagenous colitis and ulcerative colitis. Results: There was statistically significant difference in the count of neuroendocrine cells, between lymphocytic colitis and control (p=0.019104), and between ulcerative colitis and controls (p=0.0077). In collagenous colitis there was an increase in neuroendocrine cells but we failed to find statistical differences. Conclusion: We could observe neuroendocrine cell hyperplasia in lymphocytic colitis and ulcerative colitis compared with controls, which confirm previous studies.

Keywords : Colitis, lymphocytic; Colitis, collagenous; Colitis, ulcerative; Chromogranin A.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )