Abstract

LUQUEZ MINDIOLA, Adán; OTERO REGINO, William  and  SCHMULSON, Max. Diagnostic and therapeutic approach to dyspepsia and functional dyspepsia: what’s new in 2019?. Rev. gastroenterol. Perú [online]. 2019, vol.39, n.2, pp.141-152. ISSN 1022-5129.

Dyspepsia encompasses a set of symptoms that originate in the gastroduodenal region. It is characterized by pain or epigastric burning, early satiety and post-prandial fullness. According to the relationship of symptoms with meals, it is divided into epigastric pain syndrome and postprandial distress syndrome. However, in clinical practice, they frequently overlap. In recent years the paradigm of gastric physiological alterations has been changed and evidence supporting duodenal eosinophilia has increased, as a primary alteration that alters gastric physiology and can induce symptomatology. Every day there is more interest in the alteration of the microbiota. The treatment is based on the suppression of acid, neuromodulators, prokinetics, psychotherapy, alternative and complementary therapies. No treatment is effective in all patients.

Keywords : Dyspepsia; Duodenum; Gastrointestinal microbiome, Treatment.

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